Combining regional health system and policy knowledge with technical and analytic skills to deliver high-impact RWE solutions

Leveraging decades of expertise, we offer solutions for real-world data (RWD) analytics and real-world evidence (RWE) generation to meet diverse client needs across the pharmaceutical product development continuum.

Integrated Evidence Planning (IEP)

CCHO’s holistic, dynamic, and proactive approach encompasses the entire product lifecycle, from clinical development to commercialization and post-marketing activities, integrating RWE and clinical evidence generation and utilization strategies to support your clinical and commercial objectives. We ensure seamless multi-disciplinary stakeholder engagement and coordination across all activities to provide alignment of global and regional strategies. We take our clients on the RWE journey from initial evidence gap analysis and protocol design through study implementation and evidence dissemination, with the aim to establish and communicate the real-world value of their products.

Real-World Data (RWD) Analysis

Retrospective RWE studies utilize and analyze RWD collected from routine clinical practice or administrative sources to evaluate treatment outcomes, healthcare utilization patterns, and patient characteristics. In today’s world, harnessing the power of RWD has proved to be highly valuable in driving informed healthcare decisions, particularly in the setting of rare disease approvals and the support of expanded indications.

CCHO leverages a diverse range of RWD sources, including:

Electronic health records (EHRs)

Insurance billing and claims databases

Administrative and hospital databases

Established drug or disease registries

Patient-reported outcomes (PROs) and health surveys

Wearable devices and mobile health apps

Real-World Evidence (RWE) Generation

Our RWE generation services are designed to deliver robust insights into the effectiveness, safety, and value of healthcare products in real-world settings. CCHO guides you through every step of your RWE journey, starting by understanding your needs and objectives and designing the optimal study, to developing the protocol, establishing the analytical framework, identifying data sources, managing sites, patient recruitment, and data collection, and supporting in your communications needs by developing manuscripts, abstracts, and posters. We conduct various types of studies including but not limited to:

  • Prospective Drug/Disease Registries

  • Burden of Illness

  • Patient-Reported Outcomes (PROs)

  • Treatment and Population Trends

  • Cost and Healthcare Resource Utilization (HCRU) Analysis

Evidence Synthesis and Evaluation

  • Systematic and Targeted Literature Review

  • Network Meta-Analysis